Read Third Wave’s blog about San Pedro journeys, set and settings, and recovery. “Bad trips” and dysphoric symptoms are possible, but they’re likely more common for people who don’t pay attention to set and setting, or have a history of mental illness. Mescaline effects are generally felt within minutes of consumption, peaking at two to four hours and lasting for up to eight. During this time, you are likely to see closed-eye visuals of colors and patterns, such as mosaics, arabesques, and spirals. These visuals often transform into more definite objects like architecture, animals, and humans.

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As Rapéh is a tobacco-based product it is also advised to use small amounts to begin with, as larger amounts or ‘flood doses’ can trigger unpleasant feelings of nausea that can last for up to an hour. After mental preparations are complete, pour a small amount (no more than 0.25 grams for beginners) of the dry powdered tobacco into the palm or a folded piece of card and flatten any larger clumps of Rapéh with the long flat side of the Kuripe. Next, scoop half of the Rapéh into the nose end of the pipe and gently tap it with a finger to settle the powder into the Kuripe’s V-shaped elbow. At first glance, the handheld Kuripe may appear confusing with how to use it, many amusingly mistaking the ‘blow’ end for the ‘nostril’ end of the pipe. However, the Rapéh self-application process can be a simple and enjoyable experience when broken down into a step-by-step method used by many Rapéh enthusiasts. A Kuripe is a small handheld powder tobacco pipe occasionally attached to a string and worn around the neck.

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Far more than a hallucinogenic experience or “trip” shamanic work is an invitation into elevated states of consciousness and a connection to something greater than the everyday human experience. Retreat centers vary widely in their offerings, but you can expect to share meals with other retreat participants and have the ceremonial space on site. People serve themselves in spiritual clubs in Tulum, in the car on a long drive, on the go between mind-expanding events in Bali, and in other inappropriate ways and settings. I’d never had a meaningful relationship with my Grandparents because of age gaps and health issues. Then I eventually accepted I wouldn’t have a deep and meaningful relationship with the figures because… they were gone. So I embraced this unfillable hole in my heart with as much love and grace as I could muster, genuinely accepting this void would never be filled. Although Kambo is growing in popularity, there are still only a small number of practitioners relative to the global population.

Read more about Kambo Training here.

Peyote ceremonies can last upwards of 10 hours overnight and typically involve drumming, chanting, and prolonged periods of sleeplessness, along with social and behavioral interventions. They often involve prayers and spiritual practices for specific purposes, such as health and well-being, spiritual guidance for important decisions or journeys , or accepting the passing of a loved one. And many users find it helps to set up their intention in a similar way before consuming peyote, for instance by affirming their desire to learn. Peyote has also been shown to help people solve problems, access their creativity, be more environmentally conscious, and improve learning. In its original use, the plant medicine was also used to treat a number of ailments, including snake bites, wounds, skin conditions, and general pain. The effects of peyote are usually felt within 30 minutes to an hour after consumption.

A small 2019 study found that a specific form of acupuncture called Tung’s 7-point acupuncture protocol may help reduce fibroid symptoms. Nine out of the 14 study participants experienced complete elimination of all fibroid symptoms after 12 weeks of treatment, with no adverse side effects. Eating a nutritious, balanced diet and getting regular physical activity may help improve fibroid symptoms, but there is no evidence to suggest that they can shrink fibroids. If your fibroids are impacting your daily life, your healthcare provider may suggest prescription medications and/or medical procedures to shrink or remove the fibroids. For those in search of a more internal experience, some Ayahuasca retreat centers augment the effects of the experience through silence and isolation between ceremonies.

Indigenous facilitators are likely to understand how to guide people through the kambo experience in some depth, and will probably have a good anticipation of what dose is appropriate for you. They will likely have spent years training with kambo and other plant medicines, including going on challenging dietas. Some indigenous facilitators will be experienced shamans, who understand how to work with a number of plant medicines in addition to kambo.

To avoid superficial reasons for participating in an Ayahuasca ceremony, such as peer pressure, a desire to prove something to yourself, or a mere curiosity to experience the visual and hallucinatory aspects of the plant medicine. Kambo, a potent secretion derived from the Giant Monkey Frog, is known for its cleansing effects as well as strengthening the immune system. It works by rapidly eliminating toxins and ‘panema’ from the body, priming it for the deeper spiritual work with Ayahuasca. The process can be intense, but the payoff is a more balanced physical and emotional state, often described as a reset or reboot. Preparing for an Ayahuasca ceremony means not only following the dietary and lifestyle guidelines but also nurturing your emotional, mental, and spiritual well-being. This ritual has been adopted by the alternative health movement, including by people claiming to be shamanic healers in Australia, who incorporate its use as part of cleansing rituals.

Kambo is usually used in a group setting, called a Kambo circle or Kambo ceremony. The effects on humans usually include tachycardia, nausea, vomiting, and diarrhea. Peyote’s mescaline content is typically 1-6% by dry weight, tending toward the low-middle part of this range. The mescaline content of San Pedro (T. pachanoi) and Peruvian torch (T. peruvianus) is less in general. In San Pedro, mescaline content is said to range between 0.025% and 2.375% by dry weight, and Peruvian torch has been found to contain up to 0.817% mescaline by dry weight and sometimes none at all. Peyote buttons appear to retain mescaline for an exceptionally long time—potentially even thousands of years. The key is proper storage in cool, dark, dry conditions, ideally in an airtight container.

Ultimately, we don’t know enough yet about kambo to fully understand its risks. It is possible that it poses a risk of heart attack even in seemingly healthy people. Therefore a decision to take kambo should not be taken lightly – and every effort should be taken to choose a trustworthy and experienced facilitator. The first was in 2008, when a 52-year-old Brazilian man died at a private kambo ceremony.

When should I use rapé? How often? What dosage?